Fri Apr 08 2022

116 articles - From Saturday Apr 02 2022 to Friday Apr 08 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

J Neurogastroenterol Motil

Association Between Psychosocial Disorders and Gastroesophageal Reflux Disease: A Systematic Review and Meta-analysis.

Results of our meta-analysis showed that psychosocial disorders are associated with GERD; there is an interaction between the two.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

Corticosteroid plus glycyrrhizin therapy for chronic drug- or herb-induced liver injury achieves biochemical and histological improvements: A randomised open-label trial.

This study provides the first clinical evidence that corticosteroid plus glycyrrhizin therapy for chronic DILI with or without AIH-like features can achieve both biochemical response and histological improvements with good safety. (ClinicalTrials.gov, NCT02651350).

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Am J Gastroenterol

Current Applications of Telemedicine in Gastroenterology.

There has been a progressive expansion in the use of telemedicine in the field of gastroenterology, which has been accelerated by the COVID-19 pandemic. In this review, we discuss telemedicine - its history, various forms, and limitations - and its current applications in gastroenterology. Specifically, we focus on telemedicine in gastroenterology practice in general as well as specific applications, including the management of inflammatory bowel disease, celiac disease, and colorectal cancer surveillance and its use as an aid in endoscopic procedures.

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Short Bowel Syndrome in Adults.

Because patients with SBS constitute a heterogenous group, management is complex and multifaceted involving nutrition support, fluid and electrolyte management, and pharmacologic therapies in particular to control diarrhea. Surgical interventions including intestinal transplantation may be considered in selected individuals. Successful care of these patients is best accomplished by a multidisciplinary team that is experienced in the management of this syndrome.

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Endoscopy

Tube-in-tube endoscopic vacuum therapy for the closure of upper gastrointestinal fistulas, leaks, and perforations.

Three patients (10%) had adverse events and three patients (10%) died. The median time under therapy was of 19 days (range 1-70) and the median number of endoscopic sessions was 3 (range 1-9). CONCLUSIONS : This standardized approach and EVT modification using a tube-in-tube drain, with frequent fistula cleansing, were successful and safe in a wide variety of UGI wall defects.

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Gastroenterology

Effect of Helicobacter pylori Eradication on Gastric Cancer Prevention: Updated Report from a Randomized Controlled Trial with 26.5 Years of Follow-up.

Eradication of H. pylori might confer a long-term protection against gastric cancer in high-risk populations, especially for infected individuals without precancerous gastric lesions at baseline.

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Endoscopic Screening Program for Control of Esophageal Adenocarcinoma in Varied Populations: A Comparative Cost-Effectiveness Analysis.

The optimal strategy of screening differs by race and sex. White men with GERD symptoms can potentially be screened more intensely than currently recommended. Screening women is not cost-effective and may cause net harm for black women.

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Gastrointest Endosc

Disposable versus reusable gastroscope: a prospective randomized non-inferiority trial.

Given the overall safety profile and similar technical performance, disposable gastroscopes represent an alternative to reusable gastroscopes for routine examination, bedside first aid and some certain circumstances.

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Gastroparesis peroral endoscopic myotomy outcomes after 4 years of follow-up in a large cohort of patients with refractory gastroparesis.

G-POEM is an effective 4-year treatment in patients with RG, especially, in DG, posing a potential first-line therapy in these patients. However, randomized, controlled clinical trials are needed to confirm these results.

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Incidence of Sedation-Related Adverse Events during ERCP with Anesthesia Assistance: A Multicenter Observational Study.

GA for ERCP was associated with less hypoxemia, while SWPI was associated with less hypotension. Neither approach was better on the combined incidence of hypotension and hypoxemia.

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Gut

Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites.

The gut microbiota dysbiosis induced by cigarette smoke plays a protumourigenic role in CRC. The smoke-induced gut microbiota dysbiosis altered gut metabolites and impaired gut barrier function, which could activate oncogenic MAPK/ERK signalling in colonic epithelium.

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Decreased risk of treatment failure with vedolizumab and thiopurines combined compared with vedolizumab monotherapy in Crohn's disease.

Using validated methodologies, combination therapy with vedolizumab and thiopurines was associated with lower treatment failure compared with vedolizumab monotherapy in CD but not UC across the USA and France.

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Interleukin-11 drives human and mouse alcohol-related liver disease.

Pathogenic IL-11 signalling in hepatocytes plays a crucial role in the pathogenesis of ALD and could serve as an independent prognostic factor for transplant-free survival. Blocking IL-11 signalling might be a therapeutic option in human ALD, particularly AH.

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NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression.

NFATc1 stimulates NAFLD progression through chronic ER stress sensing and subsequent activation of terminal UPR signalling in hepatocytes. Interfering with ER stress-responses, for example, by TUDCA, protects fatty livers from progression towards manifest NASH.

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Role of adherent and invasive Escherichia coli in Crohn's disease: lessons from the postoperative recurrence model.

Based on the postoperative recurrence model, our data support the idea that AIEC are involved in the early steps of ileal CD.

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Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients.

Our study dissects the coordinated immune responses for different HBV infection phases and provides a rich resource for fully understanding immunopathogenesis and developing effective therapeutic strategies.

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Unfavourable intrauterine environment contributes to abnormal gut microbiome and metabolome in twins.

Dysbiotic microbiota profiles and pronounced metabolic alterations are associated with selective FGR affected by adverse intrauterine environments, emphasising the possible effects of dysbiosis on long-term neurobehavioural development.

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Hepatology

An international survey on Patterns Of Practice in Nonalcoholic Fatty Liver Disease (NAFLD) and Expectations for Therapies - the POP-NEXT Project.

This international survey revealed major deficiencies and delays in referral pathways, suboptimal screening for comorbidities or managing lifestyle modifications by SP and limited local availability for non-pharmacological interventions. Monitoring practices are not aligned with current guidelines.

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Are There Outcomes Differences Between Non-alcoholic Fatty Liver Disease (NAFLD) and Metabolic Associated Fatty Liver Disease (MAFLD)?

MAFLD and NAFLD have similar clinical profiles and long-term outcomes. The increased liver-related mortality among NAFLD is driven by IR and among MAFLD is primarily driven by ALD.

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C-X-C motif chemokine ligand 1 induced by Hedgehog signaling promotes mouse extrahepatic bile duct repair after acute injury.

HH-regulated CXCL1 orchestrates the early inflammatory response and biliary proliferation after EHBD injury through complex cellular crosstalk.

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Occludin stalls HCV particle dynamics apart from hepatocyte tight junctions, promoting virion internalization.

Although CLDN1 KO potently inhibits HCV infection, OCLN kept accumulating underneath the particle, indicating that OCLN recruitment is CLDN1-independent. Moreover, inhibition of the phosphorylation of Ezrin, a protein involved in HCV entry that links receptors to the actin cytoskeleton, increased OCLN accumulation and correlated with more efficient HCV internalization. Together, our data provide robust evidence that HCV particles interact with OCLN away from TJs and shed novel mechanistic insights regarding the manipulation of transmembrane receptor localization by extracellular virus particles.

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Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77- fibroblast growth factor 21 pathway.

Collectively, our data suggest that SBK1 is a novel regulator of the metabolic adaption against obesity via the Nur77-FGF21 pathway.

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Inflamm Bowel Dis

Association of C-reactive Protein and Partial Mayo Score With Response to Tofacitinib Induction Therapy: Results From the Ulcerative Colitis Clinical Program.

Patients who achieved clinical response at week 8 had larger decreases in CRP and PMS at week 4 than patients who did not. IndNR who achieved clinical response at week 16 with extended tofacitinib induction had a larger decrease in PMS at week 8 vs those who did not. ClinicalTrials.gov NCT00787202;NCT01465763;NCT01458951;NCT01470612.

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Divergent Adaptations in Autonomic Nerve Activity and Neuroimmune Signaling Associated With the Severity of Inflammation in Chronic Colitis.

Sympathetic activity may correlate with an adaptive mechanism to reduce the severity of chronic colitis. The Winnie and Winnie-Prolapse mouse models of moderate and severe chronic colitis are well suited to examine the pathophysiology of progressive chronic intestinal inflammation.

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Gender-Based Differences in Response to Tumor Necrosis Factor Inhibitor Therapies for Ulcerative Colitis: Individual Participant Data Meta-Analyses of Clinical Trials.

Men are less likely to achieve clinical remission, mucosal healing, and clinical response compared to women during induction treatment with TNFi for UC, but not during the maintenance phase. Future studies delineating the mechanisms underlying these observations would be informative.

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Is Salt at Fault? Dietary Salt Consumption and Inflammatory Bowel Disease.

Much attention has focused on components of the Western diet, including the high fat content, lack of fiber, added sugars, and use of additives, such as carrageenan and other emulsifiers. Less attention has been paid to the impact of high salt intake, an integral component of ultra-processed foods, which has increased dramatically in the US diet over the past 50 years. We review a growing body of literature linking the rise in dietary salt intake with the epidemiology of IBD, increased consumption of salt as a component of ultra-processed foods, high salt intake and imbalances in immune homeostasis, the effects of a high-salt diet on other inflammatory disorders, salt's impact on animal colitis models, salt as an underrecognized component in diet modification-induced remission of IBD, and directions for future investigation.

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Prevalence, Pathogenesis and Management of Anemia in Inflammatory Bowel Disease: An IG-IBD Multicenter, Prospective, and Observational Study.

In Italy, the prevalence of IBD-associated anemia is lower than previously reported. Anemia of IBD is most commonly due to iron deficiency and contributes to fatigue and poor quality of life, but remains untreated in a large proportion of patients with iron and/or vitamin deficiencies. This study is registered at clinicaltrials.gov as NCT02872376.

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Severe Activity of Inflammatory Bowel Disease is a Risk Factor for Severe COVID-19.

In this cohort of patients with IBD and SARS-CoV-2 infection, severe IBD activity was the only independent risk factor for severe COVID-19.

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Top-down Versus Step-up Strategies to Prevent Postoperative Recurrence in Crohn's Disease.

Top-down strategy should be the preferred management to prevent short and long-term postoperative recurrence in CD.

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J Crohns Colitis

Clinical Phenotypes and Outcomes in Monogenic versus Non-Monogenic Very Early Onset Inflammatory Bowel Disease.

Monogenic disease is an important driver of disease severity in VEOIBD. WES is a valuable tool in prognostication and management of VEOIBD.

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Pain characteristics in patients with inflammatory bowel disease: A monocentric cross-sectional study.

The prevalence of pain was high in IBD patients (˜75%) and higher in Crohn's patients. Significant impacts on quality of life were confirmed. More than 25% of patients with abdominal pain described CS responsible for more severe pain and worsened quality of life.

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Surgery Due to Inflammatory Bowel Disease During Pregnancy: Mothers and Offspring Outcomes From an Ecco Confer Multicentre Case Series (Scar Study).

IBD surgery during pregnancy remains an extremely serious situation. Therefore, surgical management should be performed in a multidisciplinary team, involving gastroenterologists, colorectal surgeons, obstetricians and neonatal specialists.

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J Hepatol

A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis.

Seladelpar demonstrated robust, dose-dependent, clinically significant, and durable improvements in biochemical markers of cholestasis and inflammation in PBC patients at risk for disease progression. Seladelpar appeared safe and well tolerated with no increase in pruritus.

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Blocking CD47 promotes anti-tumor immunity through CD103+ dendritic cell-NK cell axis in murine hepatocellular carcinoma model.

In addition to classical DC-T cell axis, CD47 blockade significantly enhanced the ability of tumor DNA uptake by CD103 + DCs resulting in the stimulation of the cGAS-STING pathway, which promoted the infiltration and activation of NK cells in liver cancer.

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Increased platelet aggregation in patients with decompensated cirrhosis indicates higher risk of further decompensation and death.

Our study demonstrates: 1) that platelet aggregation in patients with cirrhosis is higher than in healthy individuals; 2) that platelet aggregation in patients with decompensated cirrhosis (i. e. those who have already experienced some complications of cirrhosis) is particularly elevated and associated with risk of cirrhosis progression towards further complications and death.

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Metformin treatment rescues CD8+ T cell response to immune checkpoint inhibitor therapy in mice with NAFLD.

Our study discovered a critical regulation of CD8 + T cell metabolism in ICI therapy for liver cancer in the context of NASH, a finding with potential implications for treating liver cancer patients with NASH.

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Racial and ethnic disparities in rifaximin use and subspecialty referrals for patients with hepatic encephalopathy in the United States.

In a national cohort of patients with HE, we observed stark racial and ethnic disparities in the use of rifaximin, an approved therapy for the improvement of HE-specific outcomes. Access to gastroenterologists and cost controls may reduce disparities.

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T cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma.

Our data inform about a role of peripheral and intratumoral TEX - TRM dynamics in determining the outcomes of HCC patients. The dynamics between exhausted and liver-resident T cells have implications for immune-based diagnostics, rational patient selection and monitoring during HCC immunotherapies.

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J Neurogastroenterol Motil

Adverse Events Associated With Peroral Endoscopic Myotomy Affecting Extended Hospital Stay: A Multi-center Retrospective Study in South Korea.

In conclusion, most gas-related minor AEs do not significantly affect the patient's clinical course. However, subcutaneous emphysema and minor non-gas related AEs such as pneumonia, pain, fever, and pleural effusion can prolong the hospital stay, therefore careful observation is required. Efforts will be made to reduce major AEs that significantly prolong hospitalization.

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Association Between Body Mass Index and Functional Dyspepsia in Young Japanese People.

Among young Japanese people, BMI may be independently inversely associated with FD. Leanness may be an independent associated factor for FD in the young Japanese women.

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Development of Dilated Esophagus, Sigmoid Esophagus, and Esophageal Diverticulum in Patients With Achalasia: Japan Achalasia Multicenter Study.

The etiologies of dilated esophagus, sigmoid esophagus, and ED are considered multifactorial and different. Early diagnosis and optimal treatment of AEMDs are necessary to prevent these conditions.

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Effect of Drinking Warm Water on Esophageal Preparation Before Peroral Endoscopic Myotomy in Patients With Achalasia.

Drinking warm water dramatically reduces esophageal food retention and significantly improves the quality of esophageal preparation. This simple protocol is quite useful, safe, and cost-effective in the preparation of achalasia patients for POEM.

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Esophageal Microbiota and Nutritional Intakes in Patients With Achalasia Before and After Peroral Endoscopic Myotomy.

This study determined the unique esophageal microbial composition of patients with achalasia, and also found that the microbial composition did not significantly change after POEM in the short-term, despite a significant improvement in the nutritional intake.

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Hypnosis to Reduce Distress in Children Undergoing Anorectal Manometry: A Randomized Controlled Pilot Trial.

A brief session of hypnosis for children before ARM is an easily incorporable intervention that lowers distress levels prior to the procedure and is positively perceived by children and parents.

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Self-reported Non-celiac Gluten Sensitivity in the Korean Population: Demographic and Clinical Characteristics.

Our findings suggest that if there are gluten-related symptoms in irritable bowel syndrome, the possibility of accompanying non-celiac gluten sensitivity should be considered.

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Three-dimensional High-resolution Anorectal Manometry in Children With Non-retentive Fecal Incontinence.

Our study demonstrated lower pressure parameters in children with NRFI. In patients with normal resting pressures, 3D-HRAM may reveal segments with decreased pressures, which may play a potential role in the pathomechanism of incontinence.

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Transanal Irrigation for Neurogenic Bowel Dysfunction in Multiple Sclerosis: A Retrospective Study.

TAI is effective in NBD, especially in MS patients with initial Moderate NBD score. Improvement of voiding dysfunction following TAI confirms the pelvic organ cross-talk and the need to systematically consider and treat bowel dysfunction in MS to also improve urinary symptoms.

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Yokukansan Suppresses Gastric Hypersensitivity and Eosinophil-associated Microinflammation in Rats With Functional Dyspepsia.

YKS treatment improved gastric hypersensitivity by alleviating eosinophil-associated micro-inflammation in the gastroduodenal tract. This treatment may be considered an effective therapeutic option for epigastric pain and micro-inflammation in patients with FD.

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Neurogastroenterol Motil

Colonic volume in patients with functional constipation or irritable bowel syndrome determined by magnetic resonance imaging.

Patients with IBS-C have lower total colonic volumes and shorter colonic transit times than patients with FC. Future studies are needed to confirm that colonic volume allows objective distinction between the two conditions.

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Do we need an extra dimension? A pilot study on the use of three-dimensional anorectal manometry in children with functional constipation.

In our patient sample, 3D-ARM was associated with more discomfort without providing more useful information and even resulted in an inconsistent visualization of the RAIR.

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Duodenal cholinergic tuft cell number is increased in functional dyspepsia.

Cholinergic tuft cell density was higher in the duodenum of patients with FD and significantly correlated with eosinophil density. Further studies are needed to investigate the pathophysiological significance of tuft cells in FD and may provide valuable clues to the pathophysiology of FD.

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Gastrointestinal symptoms and the severity of COVID-19: Disorders of gut-brain interaction are an outcome.

GI symptoms are associated with a severe COVID-19 among survivors. Long-haulers may develop post-COVID-19 DGBI. Psychiatric disorders are common in post-COVID-19 DGBI.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther

Editorial: clinical impact of sofosbuvir renal toxicity-more light on the way.

Pubmed   Journal   ReadQx 

Editorial: delayed gastric emptying as an independent predictor of mortality in gastroparesis-it is clinically relevant after all!

Pubmed   Journal   ReadQx 

Editorial: does TAF have a better or worse safety profile than TDF, to treat hepatitis B?

Pubmed   Journal   ReadQx 

Editorial: is it not just PROs, but the most important individual PRO, that really matters in Crohn's disease?

Pubmed   Journal   ReadQx 

Editorial: is there a role for monitoring intermediate anti-TNF drug concentrations in IBD?

Pubmed   Journal   ReadQx 

Editorial: some of the obstacles in managing mood disorders in IBD.

Pubmed   Journal   ReadQx 

Clin Gastroenterol Hepatol

CGH Rising.

Pubmed   Journal   ReadQx 

Gastroenterology

Has the time come to say goodbye to therapeutic drug monitoring as we know it?

Pubmed   Journal   ReadQx 

Gastrointest Endosc

Although depth prediction of colorectal cancer with artificial intelligence is clinically relevant, standardization of histopathologic diagnosis should also be taken care of.

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Hepatology

Changing Epidemiology of Hepatocellular Cancer in the United States: winning the battle but it is not over yet.

Pubmed   Journal   ReadQx 

ILCs at the crossroad of innate and adaptive immunity.

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New kid on the block: Netrin-1 as a novel player in the delicate molecular network of hepatic inflammation.

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Re-tuning hepatocytes improves their functional engraftment.

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Should PNPLA3 polymorphism be performed in clinical practice in NAFLD patients to predict the risk of disease progression?

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Inflamm Bowel Dis

Response to: COVID-19 Vaccination, Willingness, Hesitancy, and Inflammatory Bowel Diseases.

Pubmed   Journal   ReadQx 

Sarcopenia as a Risk Prediction Tool in Inflammatory Bowel Disease.

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

A Step Toward Discovering the New World of Esophageal Microbiota.

Pubmed   Journal   ReadQx 

How Does Drinking Warm Water Affect Esophageal Preparation Before Peroral Endoscopic Myotomy in Patients With Achalasia?

Pubmed   Journal   ReadQx 

Three-dimensional High-resolution Anorectal Manometry Is Never Like the Last Conventional Anorectal Manometry?

Pubmed   Journal   ReadQx 

Neurogastroenterol Motil

The Clinical value of brain-gut behavioral therapies for functional esophageal disorders and symptoms.

In this issue of Neurogastroenterology and Motility, Hurtte et al add to the literature on the effectiveness of BGBT in treating functional esophageal symptoms, showing multimodal therapy with pharmacologic and non-pharmacologic approaches led to improvement in health-related quality of life. In this review, we outline the mechanistic underpinnings of BGBT and review the existing evidence for BGBT for functional esophageal disorders and symptoms. We also highlight the future research directions and challenges for scaling these therapies.

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther

Editorial: does TAF have a better or worse safety profile than TDF, to treat hepatitis B? Authors' reply.

Pubmed   Journal   ReadQx 

Editorial: is it not just PROs, but the most important individual PRO, that really matters in Crohn's disease? Authors' reply.

Pubmed   Journal   ReadQx 

Editorial: is there a role for monitoring intermediate anti-TNF drug concentrations in IBD? Authors' reply.

Pubmed   Journal   ReadQx 

Editorial: reply to delayed gastric emptying as an independent predictor of mortality in gastroparesis-it is clinically relevant after all! Authors' reply.

Pubmed   Journal   ReadQx 

Letter: inflammatory bowel disease services during the Covid-19 pandemic - authors' reply.

Pubmed   Journal   ReadQx 

Letter: inflammatory bowel disease services during the Covid-19 pandemic.

Pubmed   Journal   ReadQx 

Letter: potential selection bias in real-world comparison of ustekinumab versus vedolizumab as a second-line treatment for Crohn's disease-authors' reply.

Pubmed   Journal   ReadQx 

Letter: potential selection bias in the real-world comparison of ustekinumab versus vedolizumab as a second-line treatment for Crohn's disease.

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Letter: serum growth differentiation factor 15 predicts hepatocellular carcinoma occurrence after hepatitis C virus elimination-authors' reply.

Pubmed   Journal   ReadQx 

Letter: serum growth differentiation factor 15 predicts hepatocellular carcinoma occurrence after hepatitis C virus elimination.

Pubmed   Journal   ReadQx 

Letter: skipping breakfast is associated with an increased long-term cardiovascular mortality in metabolic dysfunction-associated fatty liver disease (MAFLD) but not in MAFLD-free individuals. Authors' reply.

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Letter: skipping breakfast is associated with an increased long-term cardiovascular mortality in metabolic dysfunction-associated fatty liver disease (MAFLD) but not MAFLD-free individuals.

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Letter: sPD-1 as a predictor for HBsAg seroclearance-shed light on inactive carriers with chronic hepatitis B. Authors' reply.

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Letter: sPD-1 as a predictor for HBsAg seroconversion-shed light on inactive carriers with chronic hepatsitis B.

Pubmed   Journal   ReadQx 

Letter: the value of quality liver biopsy before initiation of corticosteroids for severe alcoholic hepatitis-authors' reply.

Pubmed   Journal   ReadQx 

Clin Gastroenterol Hepatol

No Association Between Nonalcoholic Fatty Liver Disease and Severe COVID-19? Something We Might Ignore.

Pubmed   Journal   ReadQx 

Reply to the letter to the editor for "Low accuracy of FIB-4 and NAFLD fibrosis score for screening for liver fibrosis in the population".

Pubmed   Journal   ReadQx 

Response to "Age dependence of liver enzymes: celiac disease should also be considered" (CGH-D-22-00387).

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Response to Philips et al.

Pubmed   Journal   ReadQx 

This is in response to Letter to the Editor: "Transasal Endoscopy: Seeing is Believing" / Michiel Bronswijk, MD FEBGH.

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Gastroenterology

Reply: Gut microbiome metabolism drives the resolution of patients with COVID-19?

Pubmed   Journal   ReadQx 

Hepatology

Effect of diabetes medications and glycemic control on risk of hepatocellular cancer in patients with nonalcoholic fatty liver disease.

Pubmed   Journal   ReadQx 

Letter to the editor: Clinical Features of Patients Infected With Coronavirus Disease 2019 With Elevated Liver Biochemistries: A Multicenter, Retrospective Study.

Pubmed   Journal   ReadQx 

Letter to the editor: HBeAg expression suppressing/abolishing mutation elevated HBV DNA level in HBeAg-negative patients with chronic HBV infection.

Pubmed   Journal   ReadQx 

Letter to the Editor: The burgeoning field of Progressive Familial Intrahepatic Cholestasis.

Pubmed   Journal   ReadQx 

Response to letter to the editor from Zhou et al (Effect of diabetes medications and glycemic control on risk of hepatocellular cancer in patients with nonalcoholic fatty liver disease).

Pubmed   Journal   ReadQx 

J Hepatol

Hepatocyte specific depletion of Nnmt protects the mice from non-alcoholic steatohepatitis.

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

A Case of Sprue-like Enteropathy Associated With Valsartan and Irbesartan.

Pubmed   Journal   ReadQx 

A New Analysis for Old Problem of Bile Reflux.

Pubmed   Journal   ReadQx 

Sexual Dimorphism in the Gut Microbiome: Microgenderome or Microsexome?

Pubmed   Journal   ReadQx 

Sexual Dimorphism in the Gut Microbiome: Microgenderome or Microsexome? Author's Reply.

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Others

all remaining publications eg case reports, images of the month, etc…

Clin Gastroenterol Hepatol

Ozanimod in the Treatment of Ulcerative Colitis: Initial Real World Data from A Large Tertiary Center.

Pubmed   Journal   ReadQx 

Trends in the Incidence of Upper Gastrointestinal Cancers Show Changing Dynamics.

Pubmed   Journal   ReadQx 

Updates in Telemedicine for Gastroenterology Practices in the U.S.

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Endoscopy

The endoscopic ultrasound features of pancreatic fluid collections: appearances can be deceptive!

Pubmed   Journal   ReadQx 

Gastroenterology

A complication hanging by a thread.

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An Unexpected Finding on Screening Colonoscopy in a patient with CML.

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Challenges and opportunities in pancreatic cancer screening among high-risk individuals.

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Oral Regurgitation of a Large Esophageal Mass.

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Gastrointest Endosc

A computerized tomography negative pancreatic lesion diagnosed by EUS-imaging enhancement.

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Hookworm-induced refractory gastric ulcer.

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Mass Effect of An Intragastric Balloon Leading to Hydroureteronephrosis.

Pubmed   Journal   ReadQx 

Gut

Adenocarcinoma of the oesophagus: is it gastric cancer?

Pubmed   Journal   ReadQx 

Inflamm Bowel Dis

Unilateral Painless Vulval Swelling Presenting as an Adverse Reaction to Adalimumab.

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